Preheat your oven to 350°F and lightly grease a 9x13-inch baking dish with cooking spray. This ensures even baking and prevents sticking throughout the cooking process.
Cut chicken pieces into bite-sized chunks, roughly 1½ inches each. Season with garlic powder, onion powder, salt, and pepper for consistent flavor distribution in your tender chicken broccoli casserole.
In a large mixing bowl, combine cream of mushroom soup, chicken broth, milk, and shredded cheddar cheese. Whisk until smooth, then fold in cooked rice and broccoli florets gently to maintain texture.
Add seasoned chicken pieces to the sauce mixture and stir until everything is evenly coated. Pour the entire golden tender chicken broccoli casserole into your prepared baking dish, spreading evenly.
In a small bowl, melt butter and mix with breadcrumbs until resembling coarse sand. Sprinkle this topping across the casserole surface, covering all exposed areas for maximum crispiness.
Bake for 35 minutes until the breadcrumb topping turns golden brown and the edges begin bubbling. The casserole is ready when chicken is cooked through and broccoli is tender-crisp.
Remove from oven and let rest for 5 minutes before serving. Garnish with fresh parsley for color and brightness that balances the rich, creamy filling.